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        Rabbit Anti-ZFYVE26/Cy7 Conjugated antibody (bs-19159R-Cy7)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-19159R-Cy7
        英文名稱 Rabbit Anti-ZFYVE26/Cy7 Conjugated antibody
        中文名稱 Cy7標記的鋅指蛋白結構域ZFYVE26抗體
        別    名 DKFZp686F19106; DKFZp781H1112; FYVE domain-containing centrosomal protein; FYVE-CENT; KIAA0321; Spastic paraplegia 15 (complicated autosomal recessive); Spastizin; SPG15; ZFY26_HUMAN; ZFYVE 26; ZFYVE26; Zinc finger FYVE domain containing 26; Zinc finger FYVE domain containing protein 26; Zinc finger FYVE domain-containing protein 26.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 細胞生物  免疫學  神經生物學  鋅指蛋白  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
        產品應用
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 285kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human ZFYVE26
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. [provided by RefSeq, Oct 2008]

        Function:
        Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

        Subcellular Location:
        Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Midbody. Localizes to the centrosome during all stages of the cell cycle. Recruited to the midbody during cytokinesis by KIF13A.

        Tissue Specificity:
        Strongest expression in the adrenal gland, bone marrow, adult brain, fetal brain, lung, placenta, prostate, skeletal muscle, testis, thymus, and retina. Intermediate levels are detected in other structures, including the spinal cord.

        DISEASE:
        Spastic paraplegia 15, autosomal recessive

        Similarity:
        Contains 1 FYVE-type zinc finger.

        Database links:

        Entrez Gene: 514402 Cow

        Entrez Gene: 23503 Human

        Entrez Gene: 211978 Mouse

        Entrez Gene: 314265 Rat

        Omim: 612012 Human

        SwissProt: E1BLZ4 Cow

        SwissProt: Q68DK2 Human

        SwissProt: Q5DU37 Mouse

        SwissProt: D4A8G9 Rat

        Unigene: 98041 Human

        Unigene: 297919 Mouse

        Unigene: 16048 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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