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        Rabbit Anti-TNPO3/HRP Conjugated antibody (bs-18158R-HRP)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-18158R-HRP
        英文名稱 Rabbit Anti-TNPO3/HRP Conjugated antibody
        中文名稱 辣根過氧化物酶標記的轉運蛋白3抗體
        別    名 TNPO 3; Imp12; Importin 12; Importin-12; IPO12; MTR10A; TNPO 3; TNPO3; TNPO3_HUMAN; Transportin 3; Transportin SR; Transportin-3; Transportin-SR; TRN SR; TRN-SR; TRN-SR2; TRNSR.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 細胞生物  免疫學  信號轉導  轉錄調節因子  脂蛋白  表觀遺傳學  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
        產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 104kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human TNPO3
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]

        Function:
        Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 and SFRS2, by recognizing phosphorylated RS domains.

        Subunit:
        Interacts with phosphorylated SFRS1 and SFRS2. Interacts with NUP62 and RBM4.

        Subcellular Location:
        Cytoplasm. Nucleus.

        Database links:

        Entrez Gene: 23534 Human

        Entrez Gene: 320938 Mouse

        Omim: 610032 Human

        SwissProt: Q9Y5L0 Human

        SwissProt: Q6P2B1 Mouse

        Unigene: 193613 Human

        Unigene: 276381 Mouse

        Unigene: 304472 Mouse

        Unigene: 352219 Mouse

        Unigene: 424508 Mouse

        Unigene: 429470 Mouse

        Unigene: 439108 Mouse



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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