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        Rabbit Anti-SCARF1/BF350 Conjugated antibody (bs-17272R-BF350)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-17272R-BF350
        英文名稱 Rabbit Anti-SCARF1/BF350 Conjugated antibody
        中文名稱 BF350標記的內皮細胞清道夫受體抗體
        別    名 Acetyl LDL receptor; Endothelial cells scavenger receptor; SCARF1; Scavenger receptor class F member 1; Scavenger receptor expressed by endothelial cells 1; Scavenger receptor expressed by endothelial cells; SREC; SREC-I; SREC_HUMAN.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  細胞生物  信號轉導  細胞類型標志物  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
        產品應用 ICC=1:50-200 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 85kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human SCARF1
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

        Function:
        Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.

        Subunit:
        Heterophilic interaction with SREC2 via its extracellular domain. The heterophilic interaction is suppressed by the presence of ligand such as Ac-LDL. Interacts with AVIL (By similarity).

        Subcellular Location:
        Membrane.

        Tissue Specificity:
        Endothelial cells.

        Similarity:
        Contains 6 EGF-like domains.

        Database links:

        Entrez Gene: 8578 Human

        Omim: 607873 Human

        SwissProt: Q14162 Human

        Unigene: 647430 Human



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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