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        Rabbit Anti-PD-L1/Biotin Conjugated antibody (bs-10159R-Bio)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-10159R-Bio
        英文名稱 Rabbit Anti-PD-L1/Biotin Conjugated antibody
        中文名稱 生物素標記的程序性死亡配體1抗體
        別    名 CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed cell death 1 ligand 1; Programmed death ligand 1; RGD1566211.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  免疫學  細胞表面分子  細胞類型標志物  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, Sheep, )
        產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-F=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 32kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human CD274
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        Programmed cell death 1 ligand 1(Programmed death ligand 1; PD-L1; PDCD1 ligand 1; B7 homolog 1; B7-H1; CD274) involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production.

        Function:
        Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

        Subunit:
        Interacts with PDCD1.

        Subcellular Location:
        Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein.

        Tissue Specificity:
        Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.

        Similarity:
        Belongs to the immunoglobulin superfamily. BTN/MOG family.
        Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
        Contains 1 Ig-like V-type (immunoglobulin-like) domain.

        Database links:

        Entrez Gene: 29126 Human

        Entrez Gene: 60533 Mouse

        Entrez Gene: 499342 Rat

        Omim: 605402 Human

        SwissProt: Q9NZQ7 Human

        SwissProt: Q9EP73 Mouse

        Unigene: 521989 Human

        Unigene: 245363 Mouse

        Unigene: 228198 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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