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        Rabbit Anti-Calreticulin/PE-Cy5 Conjugated antibody (bs-5913R-PE-Cy5)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-5913R-PE-Cy5
        英文名稱 Rabbit Anti-Calreticulin/PE-Cy5 Conjugated antibody
        中文名稱 PE-Cy5標記的鈣網蛋白抗體
        別    名 Autoantigen RO; CALR; CALR protein; CALR_HUMAN; Calregulin; Calreticulin; cC1qR; CRP55; CRTC; Endoplasmic reticulum resident protein 60; ERp60; grp60; HACBP; RO; Sicca syndrome antigen A; SSA.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 細胞生物  免疫學  信號轉導  細胞表面分子  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
        產品應用 Flow-Cyt=1:50-200 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 44kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Calreticulin
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.

        Subunit:
        Monomer. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Interacts with PDIA3/ERp57 (By similarity). Interacts with NR3C1 and TRIM21. Interacts with GABARAP.

        Subcellular Location:
        Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface.

        Similarity:
        Belongs to the calreticulin family.

        Database links:

        Entrez Gene: 41166 Fruit fly (Drosophila melanogaster)

        Entrez Gene: 811 Human

        Entrez Gene: 12317 Mouse

        Entrez Gene: 100009050 Rabbit

        Entrez Gene: 64202 Rat

        Omim: 109091 Human

        SwissProt: P29413 Fruit fly (Drosophila melanogaster)

        SwissProt: P27797 Human

        SwissProt: P14211 Mouse

        SwissProt: P15253 Rabbit

        SwissProt: P18418 Rat

        Unigene: 2457 Fruit fly (Drosophila melanogaster)

        Unigene: 515162 Human

        Unigene: 1971 Mouse

        Unigene: 467043 Mouse

        Unigene: 974 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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