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        Rabbit Anti-N-cadherin/BF594 Conjugated antibody (bs-1172R-BF594)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-1172R-BF594
        英文名稱 Rabbit Anti-N-cadherin/BF594 Conjugated antibody
        中文名稱 BF594標記的N-鈣粘附分子抗體
        別    名 Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; NCAD; Neural Cadherin; Neural Cadherin.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  細胞生物  免疫學  激酶和磷酸酶  細胞粘附分子  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse, Cow,  (predicted: Rat, Pig, Danio rerio)
        產品應用 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 100kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human N-cadherin
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

        Function:
        Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

        Subcellular Location:
        Cell membrane.

        Similarity:
        Contains 5 cadherin domains.

        Database links:

        Entrez Gene: 1000 Human

        Entrez Gene: 281062 Cow

        Entrez Gene: 12558 Mouse

        Entrez Gene: 83501 Rat

        Omim: 114020 Human

        SwissProt: P19022 Human

        SwissProt: P15116 Mouse

        SwissProt: Q9Z1Y3 Rat

        Unigene: 464829 Human

        Unigene: 606106 Human

        Unigene: 257437 Mouse

        Unigene: 23200 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

        細胞粘附蛋白(Call Adhesion Protein)
        N-鈣粘附分子屬于依賴鈣離子的細胞間糖蛋白粘附分子的一部分,主要是參與細胞間同源性粘附,調控和介導細胞間相互反應。
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