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        Rabbit Anti-Amphiregulin/Cy5 Conjugated antibody (bs-3847R-Cy5)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-3847R-Cy5
        英文名稱 Rabbit Anti-Amphiregulin/Cy5 Conjugated antibody
        中文名稱 Cy5標記的雙調蛋白/結腸直腸細胞源性生長因子抗體
        別    名 AR; Colorectum cell derived growth factor; CRDGF; A REG; AR antibody; AREG; Colorectum cell derived growth factor; CRDGF; MGC13647; Schwannoma derived growth factor; SDGF; AREG_HUMAN.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  細胞生物  免疫學  神經生物學  生長因子和激素  轉錄調節因子  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse, Rat,  (predicted: Dog, Cow, Horse, Rabbit, Sheep, )
        產品應用 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 16kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Amphiregulin C-terminus
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        Amphiregulin expression is induced by phorbol ester, estrogen, androgen, and other EGFR ligands. In vitro, amphiregulin functions as an autocrine growth stimulator to drive proliferation of colon carcinoma cells, normal and oncogene-transformed mammary epithelial cells, cervical carcinoma cells, prostate cancer cells, and keratinocytes. Amphiregulin is important in the development of human placenta and murine mammary gland. It is reportedly overexpressed in human cancers of breast, colon, stomach and pancreas.

        Function:
        Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

        Subunit:
        The immature precursor interacts with CNIH.

        Subcellular Location:
        Membrane; Single-pass membrane protein.

        Similarity:
        Belongs to the amphiregulin family.
        Contains 1 EGF-like domain.

        Database links:

        Entrez Gene: 374 Human

        Entrez Gene: 727738 Human

        Entrez Gene: 11839 Mouse

        Omim: 104640 Human

        SwissProt: P15514 Human

        SwissProt: P31955 Mouse

        Unigene: 270833 Human

        Unigene: 645475 Human

        Unigene: 8039 Mouse



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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