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        Rabbit Anti-Egr1/BF488 Conjugated antibody (bs-1076R-BF488)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-1076R-BF488
        英文名稱 Rabbit Anti-Egr1/BF488 Conjugated antibody
        中文名稱 BF488標記的早期生長應答蛋白1抗體
        別    名 Egr-1; Early growth response 1; Krox-24; Ngf1; Ngfi; NGFI-A; zif-268; Egr1; A530045N19Rik; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; AT 225; AT225; Early growth response protein 1; G0S 30; G0S30; KROX 24; Krox 24 protein; KROX24; TIS 8; TIS8; Transcription factor ETR 103; Transcription factor ETR103; Transcription factor Zif 268; Transcription factor Zif268; Zfp 6; ZIF268; Zinc finger protein 225; ZNF 225; ZNF225; EGR1_HUMAN.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 細胞生物  免疫學  信號轉導  生長因子和激素  細胞周期蛋白  轉錄調節因子  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Mouse, Rat,  (predicted: Human, )
        產品應用 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 60kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Egr-1 (401-500aa)
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq].

        Function:
        Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

        Subcellular Location:
        Nucleus.

        Similarity:
        Belongs to the EGR C2H2-type zinc-finger protein family.
        Contains 3 C2H2-type zinc fingers.

        Database links:

        Entrez Gene: 1958 Human

        Entrez Gene: 13653 Mouse

        Omim: 128990 Human

        SwissProt: P18146 Human

        SwissProt: P08046 Mouse

        Unigene: 326035 Human

        Unigene: 708393 Human

        Unigene: 181959 Mouse



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

        Egr-1為即刻早期基因家族中的一個成員,是一種含3個鋅指結構的轉錄因子。有研究表明EGR-1在細胞生長分化中發揮重要作用,如在細胞周期G1-S期的轉換過程中Egr-1被誘導表達。
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