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        Rabbit Anti-CXCR5/Cy7 Conjugated antibody (bs-3598R-Cy7)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-3598R-Cy7
        英文名稱 Rabbit Anti-CXCR5/Cy7 Conjugated antibody
        中文名稱 Cy7標記的細胞表面趨化因子受體5抗體
        別    名 BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; Cxcr5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  細胞生物  免疫學  信號轉導  趨化因子  G蛋白偶聯受體  b-淋巴細胞  G蛋白信號  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human,  (predicted: Mouse, Rat, Pig, Cow, Rabbit, )
        產品應用
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 42kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human CXCR5/CD185
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.

        Function:
        Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

        Subcellular Location:
        Cell membrane; Multi-pass membrane protein.

        Tissue Specificity:
        Expression in mature B-cells and Burkitt lymphoma cells.

        Similarity:
        Belongs to the G-protein coupled receptor 1 family.

        Database links:

        Entrez Gene: 643 Human

        Entrez Gene: 12145 Mouse

        Entrez Gene: 29363 Rat

        Omim: 601613 Human

        SwissProt: P32302 Human

        SwissProt: Q04683 Mouse

        SwissProt: P34997 Rat

        Unigene: 113916 Human

        Unigene: 490637 Mouse

        Unigene: 6246 Mouse

        Unigene: 120732 Rat

        Unigene: 127121 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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