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        Rabbit Anti-SLAMF6/LY108/AP Conjugated antibody (bs-2682R-AP)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-2682R-AP
        英文名稱 Rabbit Anti-SLAMF6/LY108/AP Conjugated antibody
        中文名稱 堿性磷酸酶(AP)標記的SLAMF6抗體
        別    名 LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 免疫學  細胞表面分子  細胞類型標志物  自然殺傷細胞  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Mouse,  (predicted: Rat, )
        產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 37kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from mouse SLAMF6
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.

        Function:
        Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.

        Subunit:
        Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.

        Subcellular Location:
        Cell membrane; Single-pass type I membrane protein (Probable).

        Tissue Specificity:
        Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.

        Similarity:
        Contains 1 Ig-like (immunoglobulin-like) domain.

        Database links:

        Entrez Gene: 114836 Human

        Entrez Gene: 30925 Mouse

        Omim: 606446 Human

        SwissProt: Q96DU3 Human

        SwissProt: Q9ET39 Mouse

        Unigene: 492348 Human

        Unigene: 486404 Mouse



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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