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        Rabbit Anti-CNTNAP3 /APC Conjugated antibody (bs-11075R-APC)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-11075R-APC
        英文名稱 Rabbit Anti-CNTNAP3 /APC Conjugated antibody
        中文名稱 APC標記的接觸蛋白相關蛋白3抗體
        別    名 CASPR3; Cell recognition molecule Caspr3; CNTNAP3A; Contactin associated protein like 3; contactin associated protein-like 3B; FLJ14195; KIAA1714; CNTP3_HUMAN.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 神經生物學  細胞粘附分子  跨膜蛋白  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
        產品應用 ICC=1:50-200 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 138kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human CNTNAP3
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        CNTNAP3B is a 1,288 amino acid protein that is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.

        Function:
        The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined.

        Subcellular Location:
        Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 2: Secreted

        Similarity:
        Belongs to the neurexin family.
        Contains 2 EGF-like domains.
        Contains 1 F5/8 type C domain.
        Contains 1 fibrinogen C-terminal domain.
        Contains 4 laminin G-like domains.

        Database links:
        UniProtKB/Swiss-Prot: Q9BZ76.3

        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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