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        Rabbit Anti-EP4/AP Conjugated antibody (bs-8538R-AP)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-8538R-AP
        英文名稱 Rabbit Anti-EP4/AP Conjugated antibody
        中文名稱 堿性磷酸酶(AP)標記的前列腺素E受體蛋白4抗體
        別    名 Prostaglandin E Receptor EP4; EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER 2; PTGER 4; PTGER2; PTGER4.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 信號轉導  G蛋白偶聯受體  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human,  (predicted: Bee, )
        產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 53kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human EP4R/Prostaglandin E Receptor EP4
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

        Function:
        Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

        Subunit:
        Interacts with FEM1A.

        Subcellular Location:
        Cell membrane.

        Tissue Specificity:
        High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.

        Post-translational modifications:
        Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention.

        Similarity:
        Belongs to the G-protein coupled receptor 1 family.

        Database links:

        Entrez Gene: 5734 Human

        Entrez Gene: 19219 Mouse

        Entrez Gene: 84023 Rat

        Entrez Gene: 443222 Sheep

        Omim: 601586 Human

        SwissProt: P35408 Human

        SwissProt: P32240 Mouse

        SwissProt: P43114 Rat

        Unigene: 199248 Human

        Unigene: 18509 Mouse

        Unigene: 16062 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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