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        Rabbit Anti-Thrombospondin 2/Cy5 Conjugated antibody (bs-7524R-Cy5)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-7524R-Cy5
        英文名稱 Rabbit Anti-Thrombospondin 2/Cy5 Conjugated antibody
        中文名稱 Cy5標記的血小板反應蛋白2/凝血酶敏感蛋白2抗體
        別    名 THBS2; Thrombospondin-2; Thrombospondin2; TSP2; TSP2_HUMAN.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  心血管  細胞生物  細胞因子  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human,  (predicted: Mouse, Rat, Horse, )
        產品應用 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 128kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Thrombospondin 2
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.

        Function:
        Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.

        Subunit:
        Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin and type V collagen.

        Tissue Specificity:
        High expression in invertebral disk tissue.

        DISEASE:
        Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.

        Similarity:
        Belongs to the thrombospondin family.
        Contains 2 EGF-like domains.
        Contains 1 laminin G-like domain.
        Contains 1 TSP C-terminal (TSPC) domain.
        Contains 3 TSP type-1 domains.
        Contains 8 TSP type-3 repeats.
        Contains 1 VWFC domain.

        Database links:

        Entrez Gene: 7058 Human

        Entrez Gene: 21826 Mouse

        Entrez Gene: 292406 Rat

        Omim: 188061 Human

        SwissProt: P35440 Chicken

        SwissProt: Q95116 Cow

        SwissProt: P35442 Human

        SwissProt: Q03350 Mouse

        Unigene: 797 Chicken

        Unigene: 5522 Cow

        Unigene: 371147 Human

        Unigene: 26688 Mouse



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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