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        Rabbit Anti-Transferrin/Gold Conjugated antibody (bs-2052R-Gold)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul(10nm  15nm  35nm
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-2052R-Gold
        英文名稱 Rabbit Anti-Transferrin/Gold Conjugated antibody
        中文名稱 膠體金標記的轉鐵蛋白/血清鐵傳遞蛋白抗體
        別    名 Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin; TRFE_HUMAN; Beta-1 metal-binding globulin; Serotransferrin.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul(10nm  15nm  35nm
        研究領域 心血管  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 (predicted: Human, )
        產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 77kDa
        性    狀 Lyophilized or Liquid
        濃    度 0.4mg/ml
        免 疫 原 Full length native Transferrin protein purified from human plasma
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
        保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
        產品介紹 background:
        This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009].

        Function:
        Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

        Subunit:
        Monomer.

        Subcellular Location:
        Secreted.

        Tissue Specificity:
        Expressed by the liver and secreted in plasma.

        DISEASE:
        Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.

        Similarity:
        Belongs to the transferrin family.
        Contains 2 transferrin-like domains.

        Database links:

        Entrez Gene: 7018 Human

        Entrez Gene: 22041 Mouse

        Entrez Gene: 24825 Rat

        Omim: 190000 Human

        SwissProt: P02787 Human

        SwissProt: Q921I1 Mouse

        SwissProt: P12346 Rat

        Unigene: 518267 Human

        Unigene: 37214 Mouse

        Unigene: 91296 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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