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        Rabbit Anti-KCNK3/PE-Cy5.5 Conjugated antibody (bs-6674R-PE-Cy5.5)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-6674R-PE-Cy5.5
        英文名稱 Rabbit Anti-KCNK3/PE-Cy5.5 Conjugated antibody
        中文名稱 PE-Cy5.5標記的酸敏感鉀離子通道蛋白3抗體
        別    名 cTBAK 1; Acid sensitive potassium channel protein TASK 1; Cardiac two pore background K(+) channel; K2p3.1; OAT1; potassium channel, subfamily K, member 3; rTASK; TASK 1; TBAK1; TWIK related acid sensitive K+ channel; Two pore potassium channel KT3.1; KCNK3; TASK; TASK1; PPH4; TASK; TASK-1; TBAK1; KCNK3_HUMAN.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 神經生物學  通道蛋白  細胞膜受體  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Dog, Cow, Rabbit, Sheep, )
        產品應用 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 43kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human KCNK3
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008].

        Function:
        pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.

        Subcellular Location:
        Membrane; Multi-pass membrane protein (Potential).

        Tissue Specificity:
        Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.

        Similarity:
        Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

        Database links:

        Entrez Gene: 3777 Human

        Entrez Gene: 16527 Mouse

        Entrez Gene: 29553 Rat

        Omim: 603220 Human

        SwissProt: O14649 Human

        SwissProt: Q53SU2 Human

        SwissProt: O35111 Mouse

        SwissProt: O54912 Rat

        Unigene: 645288 Human

        Unigene: 439936 Mouse

        Unigene: 15536 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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