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        Rabbit Anti-AQP1/APC Conjugated antibody (bs-1506R-APC)
        訂購熱線:400-901-9800
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        說 明 書: 100ul  
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-1506R-APC
        英文名稱 Rabbit Anti-AQP1/APC Conjugated antibody
        中文名稱 APC標記的水通道蛋白1抗體
        別    名 AQP 1; AQP-1; AQP1_HUMAN; Aquaporin-1; Aquaporin-CHIP; Channel like integral membrane protein 28 kDa; MGC26324; Water channel protein CHIP 29; AQP CHIP; AQP1; Aquaporin CHIP; Aquaporin1; Aquaporin 1; Channel forming integral protein 28kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; Urine water channel; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule.  
        Journal
        PMID
        IF
        Application
        [IF=3.297] Fang-Hao Cai. et al. Diagnostic roles of urinary kidney microvesicles in diabetic nephropathy. Ann Transl Med. 2020 Nov; 8(21): 1431  FC ;  Human.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul  
        研究領域 腫瘤  信號轉導  通道蛋白  新陳代謝  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Sheep, )
        產品應用 IF=1:50-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 28kDa
        性    狀 Lyophilized or Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human AQP1
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
        產品介紹 background:
        Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

        Function:
        Forms a water-specific channel that provides the plasmamembranes of red cells and kidney proximal tubules with highpermeability to water, thereby permitting water to move in thedirection of an osmotic gradient.

        Subunit:
        Homotetramer. Interacts with EPHB2; involved in endolymphproduction in the inner ear (By similarity).

        Subcellular Location:
        Membrane; Multi-pass membrane protein.

        Tissue Specificity:
        Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.

        Similarity:
        Belongs to the MIP/aquaporin (TC 1.A.8) family.

        Database links:

        Entrez Gene: 358 Human

        Entrez Gene: 11826 Mouse

        Entrez Gene: 25240 Rat

        Entrez Gene: 442999 Sheep

        Entrez Gene: 282653 Cow

        Entrez Gene: 403732 Dog

        Omim: 107776 Human

        SwissProt: P47865 Cow

        SwissProt: Q9N2J4 Dog

        SwissProt: P29972 Human

        SwissProt: Q02013 Mouse

        SwissProt: P29975 Rat

        SwissProt: P56401 Sheep

        Unigene: 76152 Human

        Unigene: 18625 Mouse

        Unigene: 1618 Rat



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

        通道蛋白(Channel Protein)
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