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        Rabbit Anti-Histone H1.4 (Acetyl K53)/Gold Conjugated antibody (bs-0931R-Gold)
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
        技術支持:techsupport@bioss.com.cn
        說 明 書: 100ul(10nm  15nm  35nm
        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-0931R-Gold
        英文名稱 Rabbit Anti-Histone H1.4 (Acetyl K53)/Gold Conjugated antibody
        中文名稱 膠體金標記的乙?;M蛋白H1b抗體
        別    名 Histone H1.4(Ac-Lys53); Histone H1b (Ac-Lys53); Acetyl-Histone H1.4 (Lys53); Acetyl-Histone H1.4 (K53); HIST1H1E; H1F4; Histone H1.4; Histone H1b; H14_HUMAN; Histone H1s-4; H1 histone family member 4; H1E; Hist1h1e; Histone 1 H1e; Histone cluster 1 H1e; Histone H1; MGC116819.  
        規格價格 100ul/2980元 購買        大包裝/詢價
        說 明 書 100ul(10nm  15nm  35nm
        產品類型 乙?;贵w 
        研究領域 腫瘤  發育生物學  信號轉導  細胞凋亡  轉錄調節因子  表觀遺傳學  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, )
        產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        分 子 量 24kDa
        性    狀 Lyophilized or Liquid
        濃    度 0.4mg/ml
        免 疫 原 KLH conjugated Synthesised acetylpeptide derived from human Histone H1b around the acetylation site of Lys53
        亞    型 IgG
        純化方法 affinity purified by Protein A
        儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
        保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
        產品介紹 background:
        Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

        Function:
        Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.

        Subcellular Location:
        Nucleus. Chromosome.

        Post-translational modifications:
        Acetylated at Lys-26. Deacetylated at Lys-26 by SIRT1.

        Similarity:
        Belongs to the histone H1/H5 family.
        Contains 1 H15 (linker histone H1/H5 globular) domain.

        Database links:

        Entrez Gene: 3008 Human

        Omim: 142220 Human

        SwissProt: P10412 Human

        Unigene: 248133 Human



        Important Note:
        This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

        轉錄調節因子(Transcriptin Regulators)
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