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        Bak / Biotin (bs-22928R-Bio)  
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        100ul/2980.00元
        大包裝/詢價
        產品編號 bs-22928R-Bio
        英文名稱 Bak / Biotin
        中文名稱 生物素標記的Bcl-2同源拮抗劑抗體
        別    名 Apoptosis Regulator Bak; BAK 1; BAK; BAK like; Bak NT; BAK1; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; Bcl2 homologous antagonist killer; Bcl2 like 7 Protein; BCL2-antagonist/killer 1; BCL2L7; CDN 1; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK; BAK_HUMAN; BAK_MOUSE;   
        研究領域 免疫學  細胞凋亡  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        交叉反應
        產品應用
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 23kDa
        細胞定位 細胞漿 細胞膜 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Bak: 71-171/211 
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

        SWISS:
        O08734

        Gene ID:
        578

        Database links:
        Entrez Gene: 578 Human
        Entrez Gene: 12018 Mouse
        Omim: 600516 Human
        SwissProt: Q16611 Human
        SwissProt: Q6I9T6 Human
        SwissProt: O08734 Mouse
        Unigene: 485139 Human
        Unigene: 2443 Mouse


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