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        Rhophilin 2 Rabbit pAb (bs-19878R)  
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
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        50ul/1180.00元
        100ul/1980.00元
        200ul/2800.00元
        大包裝/詢價
        產品編號 bs-19878R
        英文名稱 Rhophilin 2 Rabbit pAb
        中文名稱 Rho結合蛋白2抗體
        別    名 76 kDa RhoB effector protein; D7Ertd784e; GTP Rho binding protein 2; GTP-Rho-binding protein 2; p76RBE; Rho GTPase binding protein 2; RhoB effector; RhoBP; Rhophilin 2; Rhophilin; Rhophilin like protein; Rhophilin like Rho GTPase binding protein; Rhophilin Rho GTPase binding protein 2; Rhophilin-2; Rhophilin2; RHPN 2; RHPN2; RHPN2_HUMAN.  
        研究領域 細胞生物  信號轉導  G蛋白信號  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
        產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 77 kDa
        檢測分子量
        細胞定位 細胞漿 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Rhophilin 2: 601-686/686 
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]

        Function:
        Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.

        Subunit:
        Interacts with GTP-bound RhoA and RhoB.

        Subcellular Location:
        Cytoplasm > perinuclear region.

        Tissue Specificity:
        Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver.

        Similarity:
        Belongs to the RHPN family.
        Contains 1 BRO1 domain.
        Contains 1 PDZ (DHR) domain.
        Contains 1 REM (Hr1) repeat.

        SWISS:
        Q8IUC4

        Gene ID:
        85415

        Database links:

        Entrez Gene: 533687 Cow

        Entrez Gene: 85415 Human

        Entrez Gene: 52428 Mouse

        Entrez Gene: 308516 Rat

        SwissProt: A4FUC9 Cow

        SwissProt: Q8IUC4 Human

        SwissProt: Q8BWR8 Mouse

        Unigene: 466435 Human

        Unigene: 286600 Mouse



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