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        SEC16A Rabbit pAb (bs-19611R)  
        訂購熱線:400-901-9800
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        50ul/1180.00元
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        200ul/2800.00元
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        產品編號 bs-19611R
        英文名稱 SEC16A Rabbit pAb
        中文名稱 轉運蛋白SEC16A抗體
        別    名 FLJ26737; KIAA0310; OTTHUMP00000022589; OTTHUMP00000022592; OTTHUMP00000022593; p250; Protein SEC16 homolog A; Protein transport protein Sec16A; RP11 413M3.10; SEC 16; SEC 16A; SC16A_HUMAN; SEC16; SEC16 homolog A(S. cerevisiae); SEC16 homolog A; SEC16L.  
        研究領域 細胞生物  信號轉導  轉運蛋白  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 (predicted: Human,Dog)
        產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 233 kDa
        檢測分子量
        細胞定位 細胞漿 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human SEC16A: 1101-1200/2179 
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]

        Function:
        Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic reticulum (tER) organization.

        Subunit:
        SEC16A and SEC16B are each present in multiple copies in a heteromeric complex. Interacts with SEC23A.

        Subcellular Location:
        Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Note=SAR1A activity is required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation.

        Tissue Specificity:
        Ubiquitous. Expressed at higher levels in the pancreas.

        Similarity:
        Belongs to the SEC16 family.

        SWISS:
        O15027

        Gene ID:
        9919

        Database links:

        Entrez Gene: 9919 Human

        Omim: 612854 Human

        SwissProt: O15027 Human



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