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        SGLT2 Rabbit pAb (bs-20084R)  
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        50ul/1180.00元
        100ul/1980.00元
        200ul/2800.00元
        大包裝/詢價
        產品編號 bs-20084R
        英文名稱 SGLT2 Rabbit pAb
        中文名稱 鈉/葡萄糖協同轉運蛋白2抗體
        別    名 Low affinity sodium glucose cotransporter; Low affinity sodium-glucose cotransporter; Na(+) glucose cotransporter 2; Na(+)/glucose cotransporter 2; OTTHUMP00000163298; SC5A2_HUMAN; SGLT 2; SLC5A 2; SLC5A2; Sodium glucose cotransporter 2; Sodium/glucose cotransporter 2; Solute carrier family 5(sodium glucose cotransporter) member 2; Solute carrier family 5(sodium/glucose transporter), member 2; Solute carrier family 5 member 2.  
        Specific References  (2)     |     bs-20084R has been referenced in 2 publications.
        [IF=2.59] Tian C et al. Short communication: A high-grain diet entails alteration in nutrient chemosensing of the rumen epithelium in goats. Animal Feed Science and Technology. Volume 262, April 2020, 114410.  IHC-P ;  
        [IF=1.974] Changxin Tian. et al. The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet. ANIM SCI J. 2022 Jan;93(1):e13754  IHC ;  Goat.  
        研究領域 腫瘤  細胞生物  轉運蛋白  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
        產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 73 kDa
        檢測分子量
        細胞定位 細胞膜 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human SGLT2: 351-450/672 <Extracellular>
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]

        Function:
        Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

        Subcellular Location:
        Membrane.

        DISEASE:
        Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.

        Similarity:
        Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

        SWISS:
        P31639

        Gene ID:
        6524

        Database links:

        Entrez Gene: 6524 Human

        Entrez Gene: 399680 Cow

        Entrez Gene: 492301 Dog

        Entrez Gene: 246787 Mouse

        Entrez Gene: 64522 Rat

        Omim: 182381 Human

        SwissProt: P31639 Human

        SwissProt: Q923I7 Mouse

        SwissProt: P26430 Rabbit

        SwissProt: P53792 Rat

        Unigene: 709195 Human

        Unigene: 38870 Mouse

        Unigene: 5887 Rat



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