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        HS3ST3A1 Rabbit pAb (bs-17390R)  
        訂購熱線:400-901-9800
        訂購郵箱:sales@bioss.com.cn
        訂購QQ:  400-901-9800
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        50ul/1180.00元
        100ul/1980.00元
        200ul/2800.00元
        大包裝/詢價
        產品編號 bs-17390R
        英文名稱 HS3ST3A1 Rabbit pAb
        中文名稱 HS3ST3A1蛋白抗體
        別    名 3-OST-3A; 30ST3A1; 3OST3A1; h3 OST 3A; h3-OST-3A; heparan sulfate(glucosamine) 3 O sulfotransferase 3A1; Heparan sulfate 3 O sulfotransferase 3A1; Heparan sulfate 3-O-sulfotransferase 3A1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 3A1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; HS3SA_HUMAN; HS3ST3A1.  
        研究領域 細胞生物  信號轉導  新陳代謝  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 (predicted: Human,Mouse,Rat)
        產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 45 kDa
        檢測分子量
        細胞定位 細胞漿 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human HS3ST3A1: 1-100/406 <Cytoplasmic>
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Jul 2008]

        Function:
        Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.

        Subcellular Location:
        Golgi apparatus membrane.

        Tissue Specificity:
        Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney.

        Similarity:
        Belongs to the sulfotransferase 1 family.

        SWISS:
        Q9Y663

        Gene ID:
        9955

        Database links:

        Entrez Gene: 9955 Human

        GenBank: NM_006042.1 Human

        Omim: 604057 Human

        SwissProt: Q9Y663 Human

        Unigene: 462270 Human



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