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        KCTD8 Rabbit pAb (bs-12087R)  
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        產品編號 bs-12087R
        英文名稱 KCTD8 Rabbit pAb
        中文名稱 鉀離子通道多聚體結構域蛋白8抗體
        別    名 BTB/POZ domain-containing protein KCTD8; KCTD8; KCTD8_HUMAN; Potassium channel tetramerisation domain containing 8.  
        研究領域 神經生物學  信號轉導  通道蛋白  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
        產品應用 WB=1:500-2000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 52 kDa
        檢測分子量
        細胞定位 細胞膜 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human KCTD8: 381-473/473 
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

        Function:
        Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

        Subunit:
        Interacts as a tetramer with GABRB1 and GABRB2 (By similarity).

        Subcellular Location:
        Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.

        Similarity:
        Contains 1 BTB (POZ) domain.

        SWISS:
        Q6ZWB6

        Gene ID:
        386617

        Database links:

        Entrez Gene: 386617 Human

        Entrez Gene: 243043 Mouse

        SwissProt: Q6ZWB6 Human

        SwissProt: Q50H33 Mouse

        Unigene: 479644 Human

        Unigene: 234821 Mouse



        產品圖片
        Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Mouse Muscle tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Rat Cerebellum tissue lysates Lane 6: Rat Stomach tissue lysates Lane 7: Rat Muscle tissue lysates Primary: Anti-KCTD8 (bs-12087R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa
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