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        ADGRE1 Rabbit pAb (bs-7058R)  
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        產品編號 bs-7058R
        英文名稱 ADGRE1 Rabbit pAb
        中文名稱 表皮生長因子樣激素受體1(EMR1)抗體
        別    名 F4/80; Adhesion G protein-coupled receptor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1; EGF like module receptor 1; EGF TM7; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone receptor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.  
        Specific References  (10)     |     bs-7058R has been referenced in 10 publications.
        [IF=9.918] Daijun Zhou. et al. An injectable miR181a-IFI6 nanoparticles promote high-quality healing of radiation-induced skin injury. MATER TODAY ADV. 2022 Aug;15:100267  FC ;  Human.  
        [IF=7.675] Tao Yang. et al. Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages. ANTIOXIDANTS-BASEL. 2022 Oct;11(10):2050  IF ;  Mouse.  
        [IF=6.93] Kwan, Karen HL, et al. ?Silver nanaoparticles alter proteoglycan expression in the promotion of tendon repair.? Nanomedicine: Nanotechnology, Biology and Medicine (2013).  IHC-P ;  Rat.  
        [IF=5.923] Liang Hu. et al. Transient Activation of Hedgehog Signaling Inhibits Cellular Senescence and Inflammation in Radiated Swine Salivary Glands through Preserving Resident Macrophages. Int J Mol Sci. 2021 Jan;22(24):13493  WB ;  Pig.  
        [IF=5.714] Ruyi Qu. et al. Glucocorticoids improve the balance of M1/M2 macrophage polarization in experimental autoimmune uveitis through the P38MAPK-MEF2C axis. INT IMMUNOPHARMACOL. 2023 Jul;120:110392  FCM ;  Rat.  
        [IF=4.396] Yosuke Asami. et al. Rat peri-implant soft tissue specifically expressed CXCL2 on titanium implant during wound healing. 2021 Nov 30  IHC ;  Rat.  
        [IF=3.36] Tsang, Yuk-Wah, et al. "Improving immunological tumor microenvironment using electro-hyperthermia followed by dendritic cell immunotherapy." BMC Cancer 15.1 (2015): 708.  IHC-P ;  Mouse.  
        [IF=2.751] Jiachen Lv. et al. Alcohol Aggravates Acute Pancreatitis by Impairing Autophagic Flux Through Activation of AMPK Signaling Pathway. 2021 Feb 08  IHC ;  Human,Rat.  
        [IF=2.435] AHMED M et al. Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting. BIOMEDICAL ENGINEERING SOCIETY.2018 Nov.  FCM ;  Mouse&Human.  
        [IF=1.632] Liu Y et al. Isolation and characterization of ovine monocyte-derived macrophages from peripheral blood.(2018)Vet Immunol Immunopathol. Nov;205:83-92.  IF ;  Sheep.  
        研究領域 免疫學  生長因子和激素  G蛋白偶聯受體  糖蛋白  G蛋白信號  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 Mouse
        產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 95 kDa
        檢測分子量
        細胞定位 細胞膜 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human ADGRE1: 701-800/886 <Extracellular>
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

        Function:
        Could be involved in cell-cell interactions.

        Subunit:
        Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.

        Subcellular Location:
        Cell membrane.

        Tissue Specificity:
        Wide expression; increased levels in peripheral blood mononuclear cells.

        Similarity:
        Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains.
        Contains 1 GPS domain.

        SWISS:
        Q14246

        Gene ID:
        2015

        Database links:

        Entrez Gene: 2015 Human

        Entrez Gene: 13733 Mouse

        Omim: 600493 Human

        SwissProt: Q14246 Human

        SwissProt: Q61549 Mouse

        Unigene: 2375 Human

        Unigene: 2254 Mouse




        產品圖片
        Paraformaldehyde-fixed, paraffin embedded Mouse Small Intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
        Paraformaldehyde-fixed, paraffin embedded Mouse Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
        Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
        Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
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