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        Carboxypeptidase H Rabbit pAb (bs-6478R)  
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        產品編號 bs-6478R
        英文名稱 Carboxypeptidase H Rabbit pAb
        中文名稱 胰羧肽酶E抗體
        別    名 Carboxypeptidase E; Carboxypeptidase-E; Carboxypeptidase H; Carboxypeptidase H precursor; CarboxypeptidaseE; CarboxypeptidaseH; CBPE_HUMAN; CPE; Cph 1; CPH; Cph1; Enkephalin convertase; Entephalin convertase; Prohormone processing carboxypeptidase; Prohormone-processing carboxypeptidase.  
        研究領域 腫瘤  細胞生物  免疫學  神經生物學  生長因子和激素  糖尿病  內分泌病  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Chicken,Dog,Horse)
        產品應用 WB=1:500-2000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 48 kDa
        檢測分子量
        細胞定位 細胞核 細胞漿 細胞膜 分泌型蛋白 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human Carboxypeptidase E: 201-300/476 
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.

        Subcellular Location:
        Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
        soform 2: Nucleus.

        Tissue Specificity:
        Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas.

        Similarity:
        Belongs to the peptidase M14 family.

        SWISS:
        P16870

        Gene ID:
        1363

        Database links:

        Entrez Gene: 1363 Human

        Entrez Gene: 12876 Mouse

        Entrez Gene: 25669 Rat

        Omim: 114855 Human

        SwissProt: P04836 Cow

        SwissProt: P16870 Human

        SwissProt: Q00493 Mouse

        SwissProt: P15087 Rat

        Unigene: 75360 Human

        Unigene: 31395 Mouse

        Unigene: 470333 Mouse

        Unigene: 7149 Rat



        產品圖片
        Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti- Carboxypeptidase H (bs-6478R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD
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