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        VILIP1 Rabbit pAb (bs-6118R)  
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        產品編號 bs-6118R
        英文名稱 VILIP1 Rabbit pAb
        中文名稱 神經視錐蛋白樣1(神經鈣蛋白)抗體
        別    名 VISL1_HUMAN; Visinin-like protein 1; Visinin like protein 1; Hippocalcin-like protein 3; visinin-like protein 1 isoform 3; Neurocalcin alpha; HLP3; HLP 3; HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1; VLP-1; VISL 1; VSNL1.  
        研究領域 腫瘤  細胞生物  神經生物學  信號轉導  結合蛋白  Alzheimer's  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 Human (predicted: Mouse,Rat,Pig,Cow,Chicken)
        產品應用 WB=1:500-2000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 22 kDa
        檢測分子量
        細胞定位 細胞漿 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human VILIP1: 121-191/191 
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

        Function:
        Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

        Tissue Specificity:
        Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).

        Similarity:
        Belongs to the recoverin family.
        Contains 4 EF-hand domains.

        SWISS:
        P62760

        Gene ID:
        7447

        Database links:

        Entrez Gene: 396189 Chicken

        Entrez Gene: 282124 Cow

        Entrez Gene: 7447 Human

        Entrez Gene: 26950 Mouse

        Entrez Gene: 24877 Rat

        Omim: 600817 Human

        SwissProt: P62764 Chicken

        SwissProt: P62763 Cow

        SwissProt: P62760 Human

        SwissProt: P62761 Mouse

        SwissProt: P62762 Rat

        Unigene: 444212 Human

        Unigene: 27005 Mouse

        Unigene: 105934 Rat



        產品圖片
        Sample: Recombinant human VILIP1 protein at 100 ng Primary: Anti-VILIP1 (bs-6118R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 20 kD
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