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        CXCR5 Rabbit pAb (bs-3598R)  
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        產品編號 bs-3598R
        英文名稱 CXCR5 Rabbit pAb
        中文名稱 細胞表面趨化因子受體5(CD185)抗體
        別    名 BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15.  
        Specific References  (3)     |     bs-3598R has been referenced in 3 publications.
        [IF=5.215] Tianrui Zhang. et al. Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization. PHARMACEUTICALS-BASE. 2023 Feb;16(2):243  WB ;  Rat.  
        [IF=3.23] Huang, Hu, et al. "Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice." PloS one 12.3 (2017): e0173716.  WB, IHC-F ;  Mouse.  
        [IF=1.26] Gong, Qiaoqiao, et al. "Increased levels of CCR7 (lo) PD?1 (hi) CXCR5+ CD4+ T cells, and associated factors Bcl?6, CXCR5, IL?21 and IL?6 contribute to repeated implantation failure." Experimental and Therapeutic Medicine 14.6 (2017): 5931-5941.  IHC-P ;  Human.  
        研究領域 腫瘤  細胞生物  免疫學  信號轉導  趨化因子  G蛋白偶聯受體  b-淋巴細胞  G蛋白信號  
        抗體來源 Rabbit
        克隆類型 Polyclonal
        克 隆 號
        交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Cow)
        產品應用 WB=1:500-2000
        not yet tested in other applications.
        optimal dilutions/concentrations should be determined by the end user.
        理論分子量 45 kDa
        檢測分子量
        細胞定位 細胞膜 
        性    狀 Liquid
        濃    度 1mg/ml
        免 疫 原 KLH conjugated synthetic peptide derived from human CXCR5/CD185: 281-372/372 <Cytoplasmic>
        亞    型 IgG
        純化方法 affinity purified by Protein A
        緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
        保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
        注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
        PubMed PubMed
        產品介紹 This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

        Function:
        Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

        Subcellular Location:
        Cell membrane; Multi-pass membrane protein.

        Tissue Specificity:
        Expression in mature B-cells and Burkitt lymphoma cells.

        Similarity:
        Belongs to the G-protein coupled receptor 1 family.

        SWISS:
        P32302

        Gene ID:
        643

        Database links:

        Entrez Gene: 643 Human

        Entrez Gene: 12145 Mouse

        Entrez Gene: 29363 Rat

        Omim: 601613 Human

        SwissProt: P32302 Human

        SwissProt: Q04683 Mouse

        SwissProt: P34997 Rat

        Unigene: 113916 Human

        Unigene: 490637 Mouse

        Unigene: 6246 Mouse

        Unigene: 120732 Rat

        Unigene: 127121 Rat



        產品圖片
        Sample: Raji cell(human) Lysate at 40 ug Lymph node(mouse)Lysate at 40 ug Primary: Anti-CXCR5 (bs-3598R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42kD Observed band size: 42 kD
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